Antigen testing for COVID-19 asymptomatic screening: (Record no. 41471)

MARC details
000 -LEADER
fixed length control field 02206cam a2200145 4500
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name MULLINAX Ross A
245 ## - TITLE STATEMENT
Title Antigen testing for COVID-19 asymptomatic screening:
Remainder of title why it should be preferred over PCR insights from navy region Japan's experience with a comprehensive antigen testing strategy /
Statement of responsibility, etc. Ross A Mullinax
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Date of publication, distribution, etc. 2022
520 ## - SUMMARY, ETC.
Summary, etc. Polymerase chain reaction (PCR) is commonly used in asymptomatic screening testing, but is suboptimal for this purpose as it will identify many old persistent positives that are no longer infectious. This can result in placement of individuals that are not infectious to others into isolation. This results in substantial adverse impact to military manning and operations, without any benefit to public health. Antigen testing does not have this same drawback. Antigen testing, while less sensitive than PCR, will identify the vast majority of infectious positives, especially those with higher viral loads that are more likely to transmit to others. Importantly, use of antigen testing will also greatly increase the certainty of benefit from isolation, reducing the risk of isolating those individuals who are beyond their infectious period and pose no threat to public health. The literature on this topic is reviewed, with particular focus on studies that perform viral culture in addition to PCR and antigen testing. This allows for determination of sensitivity for infectious virus. Also, Navy Region Japan's experience with a comprehensive antigen testing strategy is described. The challenges presented by persistent positive PCR test results are examined, as well as the real-world benefits from implementing widespread use of antigen testing.
598 ## - BULLETIN HEADING
Bulletin Heading COVID-19, MILITARY, HEALTH
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYMERASE CHAIN REACTION
General subdivision ANTIGENS
-- MILITARY PERSONNEL
-- VIRAL LOAD RESULT
-- PUBLIC HEALTH MEDICINE
-- VIRUSES
-- PERSISTENCE
-- RISK REDUCTION
-- VIRAL CULTURE
-- LABORATORY TEST FINDING
-- NAVY
-- COVID-19
Geographic subdivision JAPAN
773 ## - HOST ITEM ENTRY
Main entry heading Military Medicine: International Journal of AMSUS :
Related parts Vol 187 Issue 3/4, March/April 2022, pp.68-72 (72)
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://academic.oup.com/milmed/article/187/3-4/68/6360366">https://academic.oup.com/milmed/article/187/3-4/68/6360366</a>
Public note Click here for full text
945 ## - LOCAL PROCESSING INFORMATION (OCLC)
i 67417.1001
r Y
s Y
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Total checkouts Full call number Barcode Date last seen Copy number Price effective from Koha item type
          Mindef Library & Info Centre Mindef Library & Info Centre Journals 29/07/2022   COVID-19 67417.1001 03/01/2024 1 03/01/2024 Journal Article